Can she restart her medication even though she has been off for 1 month?

Maria is a 19-year-old exchange student from Brazil. She was started on daily isoniazid (INH) 4 months ago for latent tuberculosis (TB). She would like to be seen at your clinic now because it is closer to school. She has not taken her medication for 4 weeks and cannot recall when her labs were drawn last. She has no other health history and does not take any other medications. According to the national guidelines, how long would Maria likely need to take INH? Can she restart her medication even though she has been off for 1 month? How often should she be seen for follow-up? What are the black box warnings of INH?

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